EGFR is detected as a mutational cancer driver
EGFR reports
Gene details
EGFR |
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Ensembl ID
ENSG00000146648
Transcript ID ENST00000275493 Protein ID ENSP00000275493 |
Cancer types where is driver
9
Cohorts where is driver 19 Mutated samples 642 Mutations 1,340 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
GBM (Glioblastoma Multiforme) | 10881 | 1508 | 13.86 |
LGG (Low-Grade Glioma, NOS) | 10881 | 1692 | 15.55 |
LUAD (Lung Adenocarcinoma) | 10881 | 767 | 7.05 |
LUNG_CANCER (Lung) | 10881 | 197 | 1.81 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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