CTNNB1 is detected as a mutational cancer driver
CTNNB1 reports
Gene details
CTNNB1 |
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Ensembl ID
ENSG00000168036
Transcript ID ENST00000645320 Protein ID ENSP00000495360 |
Cancer types where is driver
17
Cohorts where is driver 45 Mutated samples 879 Mutations 1,214 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
HC (Hepatocellular Carcinoma) | 7020 | 233 | 3.32 |
LUAD (Lung Adenocarcinoma) | 7020 | 321 | 4.57 |
LUNG_CANCER (Lung) | 7020 | 207 | 2.95 |
PIA (Pilocytic Astrocytoma) | 7020 | 144 | 2.05 |
PRAD (Prostate Adenocarcinoma) | 7020 | 280 | 3.99 |
UCEC (Endometrial Carcinoma) | 7020 | 89 | 1.27 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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