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DNMT3A is detected as a mutational cancer driver

DNMT3A reports

Gene details
DNMT3A
Ensembl ID ENSG00000119772
Transcript ID ENST00000264709
Protein ID ENSP00000264709
Cancer types where is driver 9
Cohorts where is driver 13
Mutated samples 124
Mutations 533
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence