SMAD4 is detected as a mutational cancer driver
SMAD4 reports
Gene details
SMAD4 |
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Ensembl ID
ENSG00000141646
Transcript ID ENST00000342988 Protein ID ENSP00000341551 |
Cancer types where is driver
13
Cohorts where is driver 35 Mutated samples 552 Mutations 872 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
COREAD (Colorectal Adenocarcinoma) | 4959 | 1319 | 26.60 |
ESCA (Esophageal Adenocarcinoma) | 4959 | 706 | 14.24 |
PAAD (Pancreatic Adenocarcinoma) | 4959 | 1357 | 27.36 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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