IntOGen - AKAP9 gene cancer mutations

AKAP9 is detected as a mutational cancer driver

AKAP9 reports

Methods
Mutation distribution

Gene details

AKAP9
Ensembl ID ENSG00000127914 Transcript ID ENST00000356239 Protein ID ENSP00000348573
Cancer types where is driver 7 Cohorts where is driver 8 Mutated samples 81 Mutations 1,206
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence