Top

CASP8 is detected as a mutational cancer driver

CASP8 reports

Gene details
CASP8
Ensembl ID ENSG00000064012
Transcript ID ENST00000358485
Protein ID ENSP00000351273
Cancer types where is driver 9
Cohorts where is driver 16
Mutated samples 180
Mutations 442
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence