NRAS is detected as a mutational cancer driver
NRAS reports
Gene details
NRAS |
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Ensembl ID
ENSG00000213281
Transcript ID ENST00000369535 Protein ID ENSP00000358548 |
Cancer types where is driver
19
Cohorts where is driver 38 Mutated samples 820 Mutations 1,026 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
ALL (Acute Lymphoblastic Leukemia) | 1692 | 48 | 2.84 |
AML (Acute Myeloid Leukemia) | 1692 | 48 | 2.84 |
COREAD (Colorectal Adenocarcinoma) | 1692 | 48 | 2.84 |
CM (Melanoma) | 1692 | 31 | 1.83 |
MM (Plasma Cell Myeloma) | 1692 | 48 | 2.84 |
THCA (Well-Differentiated Thyroid Cancer) | 1692 | 48 | 2.84 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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