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PTPRU is detected as a mutational cancer driver

PTPRU reports

Gene details
PTPRU
Ensembl ID ENSG00000060656
Transcript ID ENST00000345512
Protein ID ENSP00000334941
Cancer types where is driver 1
Cohorts where is driver 1
Mutated samples 16
Mutations 598
Mode of action Loss of function
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence