ERBB2 is detected as a mutational cancer driver
ERBB2 reports
Gene details
ERBB2 |
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Ensembl ID
ENSG00000141736
Transcript ID ENST00000269571 Protein ID ENSP00000269571 |
Cancer types where is driver
12
Cohorts where is driver 26 Mutated samples 351 Mutations 843 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder Urothelial Carcinoma) | 11286 | 4540 | 40.23 |
BRCA (Invasive Breast Carcinoma) | 11286 | 2532 | 22.43 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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