BRAF is detected as a mutational cancer driver
BRAF reports
Gene details
BRAF |
---|
Ensembl ID
ENSG00000157764
Transcript ID ENST00000496384 Protein ID ENSP00000419060 |
Cancer types where is driver
22
Cohorts where is driver 52 Mutated samples 1,416 Mutations 1,786 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
---|
In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
COREAD (Colorectal Adenocarcinoma) | 6885 | 244 | 3.54 |
LUAD (Lung Adenocarcinoma) | 6885 | 333 | 4.84 |
LUNG_CANCER (Lung) | 6885 | 108 | 1.57 |
CM (Melanoma) | 6885 | 82 | 1.19 |
MM (Plasma Cell Myeloma) | 6885 | 121 | 1.76 |
THCA (Well-Differentiated Thyroid Cancer) | 6885 | 6 | 0.09 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
---|