Top
ZZEF1 has not been detected as a mutational cancer driver

ZZEF1
Ensembl id ENSG00000074755
Mutated samples
Coding Sequence 130 (1.9%)
Protein Affecting 94 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZZEF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 40 28 7.59
Lung adenocarcinoma No 11 10 2.56
Stomach adenocarcinoma No 8 8 4.97
Uterine corpus endometrioid carcinoma No 10 7 3.04
Head and neck squamous cell carcinoma No 13 7 1.87
Bladder carcinoma No 6 6 6.12
Breast carcinoma No 7 6 0.52
Renal clear cell carcinoma No 8 6 1.44
Esophageal carcinoma No 6 4 2.74
Prostate adenocarcinoma No 6 3 1.23
Lung squamous cell carcinoma No 3 2 1.15
Lower grade glioma No 2 2 1.18
Small cell lung carcinoma No 2 2 2.90
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 2 1 1.45
Serous ovarian adenocarcinoma No 2 1 0.32
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence