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ZNF236 has not been detected as a mutational cancer driver

ZNF236
Ensembl id ENSG00000130856
Mutated samples
Coding Sequence 129 (1.9%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF236 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 16 4.34
Lung squamous cell carcinoma No 18 15 8.62
Lung adenocarcinoma No 14 12 3.07
Stomach adenocarcinoma No 14 10 6.21
Head and neck squamous cell carcinoma No 8 8 2.13
Serous ovarian adenocarcinoma No 7 6 1.90
Breast carcinoma No 7 5 0.44
Uterine corpus endometrioid carcinoma No 8 5 2.17
Esophageal carcinoma No 4 4 2.74
Bladder carcinoma No 5 3 3.06
Glioblastoma multiforme No 3 3 0.79
Small cell lung carcinoma No 2 2 2.90
Acute lymphocytic leukemia No 2 2 1.64
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 1 1 0.31
Prostate adenocarcinoma No 3 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence