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ZFP36 has not been detected as a mutational cancer driver

ZFP36
Ensembl id ENSG00000128016
Mutated samples
Coding Sequence 19 (0.3%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZFP36 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 4 3 0.80
Lung adenocarcinoma No 3 2 0.51
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Cutaneous melanoma No 1 1 0.27
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Bladder carcinoma No 1 0 0.00
Breast carcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence