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ZC3H7B has not been detected as a mutational cancer driver

ZC3H7B
Ensembl id ENSG00000100403
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 42 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZC3H7B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 13 3.52
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 5 4 0.35
Uterine corpus endometrioid carcinoma No 5 4 1.74
Head and neck squamous cell carcinoma No 7 4 1.07
Lung squamous cell carcinoma No 4 2 1.15
Serous ovarian adenocarcinoma No 3 2 0.63
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence