ZBTB7A has not been detected as a mutational cancer driver
| ZBTB7A |
|---|
| Ensembl id ENSG00000178951 |
| Mutated samples
Coding Sequence 27 (0.4%) Protein Affecting 16 (0.2%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZBTB7A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Cutaneous melanoma | No | 6 | 3 | 0.81 |
| Lung squamous cell carcinoma | No | 2 | 2 | 1.15 |
| Stomach adenocarcinoma | No | 2 | 2 | 1.24 |
| Esophageal carcinoma | No | 4 | 2 | 1.37 |
| Hepatocarcinoma | No | 2 | 1 | 1.11 |
| Bladder carcinoma | No | 2 | 1 | 1.02 |
| Pancreas adenocarcinoma | No | 1 | 1 | 0.47 |
| Renal clear cell carcinoma | No | 1 | 1 | 0.24 |
| Colorectal adenocarcinoma | No | 1 | 1 | 0.44 |
| Head and neck squamous cell carcinoma | No | 1 | 1 | 0.27 |
| Diffuse B cell lymphoma | No | 1 | 1 | 4.35 |
| Prostate adenocarcinoma | No | 1 | 0 | 0.00 |
| Medulloblastoma | No | 1 | 0 | 0.00 |
| Neuroblastoma | No | 1 | 0 | 0.00 |
| Uterine corpus endometrioid carcinoma | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|