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XDH has not been detected as a mutational cancer driver

XDH
Ensembl id ENSG00000158125
Mutated samples
Coding Sequence 150 (2.2%)
Protein Affecting 106 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all XDH gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 64 46 12.47
Lung adenocarcinoma No 13 9 2.30
Lung squamous cell carcinoma No 10 8 4.60
Breast carcinoma No 7 7 0.61
Stomach adenocarcinoma No 10 7 4.35
Glioblastoma multiforme No 5 4 1.06
Esophageal carcinoma No 4 4 2.74
Bladder carcinoma No 4 3 3.06
Uterine corpus endometrioid carcinoma No 4 3 1.30
Head and neck squamous cell carcinoma No 7 3 0.80
Renal clear cell carcinoma No 3 2 0.48
Lower grade glioma No 2 2 1.18
Small cell lung carcinoma No 2 2 2.90
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 2 1 0.47
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 4 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence