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WRN is detected as a mutational cancer driver

WRN reports

Gene details
WRN
Ensembl ID ENSG00000165392
Transcript ID ENST00000298139
Protein ID ENSP00000298139
Cancer types where is driver 1
Cohorts where is driver 1
Mutated samples 2
Mutations 292
Mode of action Loss of function
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence