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USP6 × Acute Myeloid Leukemia ×

USP6 is detected as a mutational cancer driver in Acute Myeloid Leukemia

USP6 reports in Acute Myeloid Leukemia (AML)

Cancer type details
Acute Myeloid Leukemia
Cohorts 9
Samples 661
Mutations 295,755
Driver genes 62
Gene details
USP6
Ensembl ID ENSG00000129204
Transcript ID ENST00000574788
Protein ID ENSP00000460380
Cohorts where is driver 1
Mutated samples 6
Mutated samples (%) 0.91
Mutations 11
Mode of action Activating
Known driver False
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence