Top
TUSC3 has not been detected as a mutational cancer driver

TUSC3
Ensembl id ENSG00000104723
Mutated samples
Coding Sequence 80 (1.2%)
Protein Affecting 46 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TUSC3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 8 8 2.05
Cutaneous melanoma No 16 8 2.17
Stomach adenocarcinoma No 9 7 4.35
Head and neck squamous cell carcinoma No 5 5 1.33
Colorectal adenocarcinoma No 3 3 1.31
Glioblastoma multiforme No 4 3 0.79
Serous ovarian adenocarcinoma No 2 2 0.63
Esophageal carcinoma No 4 2 1.37
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 3 1 0.09
Lung squamous cell carcinoma No 2 1 0.57
Renal clear cell carcinoma No 2 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 2 1 3.23
Small cell lung carcinoma No 1 1 1.45
Chronic lymphocytic leukemia No 14 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence