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TPTE2 has not been detected as a mutational cancer driver

TPTE2
Ensembl id ENSG00000132958
Mutated samples
Coding Sequence 113 (1.7%)
Protein Affecting 82 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TPTE2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 43 33 8.94
Lung squamous cell carcinoma No 8 7 4.02
Glioblastoma multiforme No 7 7 1.85
Prostate adenocarcinoma No 5 4 1.65
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 4 4 0.35
Renal clear cell carcinoma No 4 4 0.96
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 3 3 1.86
Neuroblastoma No 2 2 0.95
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 6 2 0.53
Bladder carcinoma No 3 1 1.02
Acute myeloid leukemia No 1 1 0.51
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Small cell lung carcinoma No 3 1 1.45
Esophageal carcinoma No 3 1 0.68
Chronic lymphocytic leukemia No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence