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TNRC6C has not been detected as a mutational cancer driver

TNRC6C
Ensembl id ENSG00000078687
Mutated samples
Coding Sequence 80 (1.2%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TNRC6C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 16 4.34
Head and neck squamous cell carcinoma No 10 9 2.40
Lung adenocarcinoma No 7 6 1.53
Breast carcinoma No 6 5 0.44
Glioblastoma multiforme No 4 4 1.06
Bladder carcinoma No 3 3 3.06
Renal clear cell carcinoma No 3 3 0.72
Lung squamous cell carcinoma No 2 2 1.15
Neuroblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 7 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence