TMA16 has not been detected as a mutational cancer driver

Ensembl id ENSG00000198498
Mutated samples
Coding Sequence 17 (0.3%)
Protein Affecting 10 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TMA16 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 2 2 1.24
Lung adenocarcinoma No 1 1 0.26
Hepatocarcinoma No 2 1 1.11
Breast carcinoma No 2 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Small cell lung carcinoma No 1 1 1.45
Renal clear cell carcinoma No 1 0 0.00
Cutaneous melanoma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence