TIAL1 has not been detected as a mutational cancer driver

Ensembl id ENSG00000151923
Mutated samples
Coding Sequence 26 (0.4%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TIAL1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 3 3 0.26
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 5 2 1.24
Head and neck squamous cell carcinoma No 4 2 0.53
Hepatocarcinoma No 2 1 1.11
Cutaneous melanoma No 3 1 0.27
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Lung adenocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence