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TFDP1 is detected as a mutational cancer driver in 1 cancer type: Uterine corpus endometrioid carcinoma and in the PAN-cancer analysis

TFDP1
Ensembl id ENSG00000198176
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 37 (0.5%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
UCEC F
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TFDP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 7 7 1.79
Uterine corpus endometrioid carcinoma Yes 7 7 3.04
Cutaneous melanoma Yes 9 4 1.08
Head and neck squamous cell carcinoma Yes 4 4 1.07
Breast carcinoma Yes 3 3 0.26
Lung squamous cell carcinoma Yes 3 3 1.72
Stomach adenocarcinoma Yes 3 3 1.86
Serous ovarian adenocarcinoma Yes 2 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence