TERF2 has not been detected as a mutational cancer driver
| TERF2 |
|---|
| Ensembl id ENSG00000132604 |
| Mutated samples
Coding Sequence 31 (0.5%) Protein Affecting 16 (0.2%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TERF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Breast carcinoma | No | 6 | 4 | 0.35 |
| Stomach adenocarcinoma | No | 4 | 3 | 1.86 |
| Bladder carcinoma | No | 2 | 2 | 2.04 |
| Cutaneous melanoma | No | 7 | 2 | 0.54 |
| Esophageal carcinoma | No | 2 | 2 | 1.37 |
| Uterine corpus endometrioid carcinoma | No | 2 | 1 | 0.43 |
| Colorectal adenocarcinoma | No | 2 | 1 | 0.44 |
| Head and neck squamous cell carcinoma | No | 3 | 1 | 0.27 |
| Hepatocarcinoma | No | 1 | 0 | 0.00 |
| Pancreas adenocarcinoma | No | 1 | 0 | 0.00 |
| Renal clear cell carcinoma | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|