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TENM3 has not been detected as a mutational cancer driver

TENM3
Ensembl id ENSG00000218336
Mutated samples
Coding Sequence 261 (3.8%)
Protein Affecting 188 (2.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TENM3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 106 85 23.04
Lung adenocarcinoma No 23 17 4.35
Lung squamous cell carcinoma No 21 16 9.20
Uterine corpus endometrioid carcinoma No 13 13 5.65
Stomach adenocarcinoma No 14 9 5.59
Breast carcinoma No 9 7 0.61
Head and neck squamous cell carcinoma No 7 7 1.87
Esophageal carcinoma No 7 7 4.79
Glioblastoma multiforme No 9 6 1.58
Bladder carcinoma No 9 5 5.10
Colorectal adenocarcinoma No 4 4 1.75
Renal clear cell carcinoma No 4 3 0.72
Hepatocarcinoma No 3 2 2.22
Prostate adenocarcinoma No 3 1 0.41
Acute myeloid leukemia No 1 1 0.51
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 2 1 4.35
Acute lymphocytic leukemia No 1 1 0.82
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 17 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence