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STIP1 mutations in 5 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Breast carcinoma, Uterine corpus endometrioid carcinoma, Stomach adenocarcinoma, Head and neck squamous cell carcinoma

STIP1
Ensembl id ENSG00000168439
Mutated samples
Coding Sequence 36 (0.5%)
Protein Affecting 25 (0.4%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all STIP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 6 5 1.28
Uterine corpus endometrioid carcinoma Yes 5 3 1.30
Stomach adenocarcinoma Yes 3 3 1.86
Breast carcinoma Yes 3 2 0.17
Head and neck squamous cell carcinoma Yes 3 2 0.53
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 2 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Cutaneous melanoma No 3 1 0.27
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence