SRCAP has not been detected as a mutational cancer driver
| SRCAP |
|---|
| Ensembl id ENSG00000080603 |
| Mutated samples
Coding Sequence 209 (3.1%) Protein Affecting 161 (2.4%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SRCAP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Cutaneous melanoma | No | 54 | 40 | 10.84 |
| Lung adenocarcinoma | No | 20 | 18 | 4.60 |
| Breast carcinoma | No | 20 | 15 | 1.31 |
| Head and neck squamous cell carcinoma | No | 18 | 13 | 3.47 |
| Stomach adenocarcinoma | No | 16 | 12 | 7.45 |
| Lung squamous cell carcinoma | No | 13 | 11 | 6.32 |
| Bladder carcinoma | No | 11 | 10 | 10.20 |
| Uterine corpus endometrioid carcinoma | No | 8 | 6 | 2.61 |
| Small cell lung carcinoma | No | 5 | 5 | 7.25 |
| Chronic lymphocytic leukemia | No | 4 | 4 | 1.38 |
| Colorectal adenocarcinoma | No | 6 | 4 | 1.75 |
| Prostate adenocarcinoma | No | 4 | 3 | 1.23 |
| Thyroid carcinoma | No | 3 | 3 | 0.93 |
| Serous ovarian adenocarcinoma | No | 5 | 3 | 0.95 |
| Glioblastoma multiforme | No | 4 | 3 | 0.79 |
| Hepatocarcinoma | No | 3 | 2 | 2.22 |
| Renal clear cell carcinoma | No | 7 | 2 | 0.48 |
| Neuroblastoma | No | 2 | 2 | 0.95 |
| Esophageal carcinoma | No | 2 | 2 | 1.37 |
| Pancreas adenocarcinoma | No | 1 | 1 | 0.47 |
| Lower grade glioma | No | 1 | 1 | 0.59 |
| Diffuse B cell lymphoma | No | 1 | 1 | 4.35 |
| Non small cell lung carcinoma | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|