SOS1 is detected as a mutational cancer driver

SOS1 reports

Gene details
Ensembl ID ENSG00000115904
Transcript ID ENST00000426016
Protein ID ENSP00000387784
Cancer types where is driver 1
Cohorts where is driver 1
Mutated samples 15
Mutations 266
Mode of action Activating
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence