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SLITRK1 has not been detected as a mutational cancer driver

SLITRK1
Ensembl id ENSG00000178235
Mutated samples
Coding Sequence 165 (2.4%)
Protein Affecting 112 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLITRK1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 49 31 8.40
Lung adenocarcinoma No 24 21 5.37
Stomach adenocarcinoma No 19 9 5.59
Colorectal adenocarcinoma No 11 8 3.49
Esophageal carcinoma No 8 7 4.79
Breast carcinoma No 7 6 0.52
Lung squamous cell carcinoma No 12 6 3.45
Head and neck squamous cell carcinoma No 8 6 1.60
Uterine corpus endometrioid carcinoma No 4 4 1.74
Renal clear cell carcinoma No 3 3 0.72
Prostate adenocarcinoma No 2 2 0.82
Serous ovarian adenocarcinoma No 4 2 0.63
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 4 1 1.11
Acute myeloid leukemia No 1 1 0.51
Thyroid carcinoma No 2 1 0.31
Medulloblastoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence