Top
SLC38A6 has not been detected as a mutational cancer driver

SLC38A6
Ensembl id ENSG00000139974
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 21 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC38A6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 9 4 1.08
Small cell lung carcinoma No 3 3 4.35
Lung adenocarcinoma No 3 2 0.51
Hepatocarcinoma No 2 2 2.22
Bladder carcinoma No 2 2 2.04
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 3 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 5 1 0.62
Head and neck squamous cell carcinoma No 3 1 0.27
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Glioblastoma multiforme No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence