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SEMA7A has not been detected as a mutational cancer driver

SEMA7A
Ensembl id ENSG00000138623
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SEMA7A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 6 6 2.61
Breast carcinoma No 6 4 0.35
Stomach adenocarcinoma No 5 4 2.48
Lung adenocarcinoma No 5 3 0.77
Thyroid carcinoma No 3 3 0.93
Cutaneous melanoma No 8 2 0.54
Lung squamous cell carcinoma No 2 1 0.57
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 2 1 0.26
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence