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RNF213 × Lung Squamous Cell Carcinoma ×

RNF213 is detected as a mutational cancer driver in Lung Squamous Cell Carcinoma

RNF213 reports in Lung Squamous Cell Carcinoma (LUSC)

Cancer type details
Lung Squamous Cell Carcinoma
Cohorts 6
Samples 703
Mutations 4,282,647
Driver genes 75
Gene details
RNF213
Ensembl ID ENSG00000173821
Transcript ID ENST00000582970
Protein ID ENSP00000464087
Cohorts where is driver 1
Mutated samples 2
Mutated samples (%) 0.28
Mutations 61
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence