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RASGRF1 has not been detected as a mutational cancer driver

RASGRF1
Ensembl id ENSG00000058335
Mutated samples
Coding Sequence 119 (1.8%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RASGRF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 40 23 6.23
Head and neck squamous cell carcinoma No 12 8 2.13
Lung squamous cell carcinoma No 12 6 3.45
Breast carcinoma No 8 5 0.44
Uterine corpus endometrioid carcinoma No 5 5 2.17
Colorectal adenocarcinoma No 6 5 2.18
Hepatocarcinoma No 5 3 3.33
Renal clear cell carcinoma No 4 3 0.72
Small cell lung carcinoma No 3 3 4.35
Glioblastoma multiforme No 4 3 0.79
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 2 2 2.04
Serous ovarian adenocarcinoma No 2 2 0.63
Lung adenocarcinoma No 3 1 0.26
Neuroblastoma No 1 1 0.48
Stomach adenocarcinoma No 5 1 0.62
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Medulloblastoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence