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RABEP1 has not been detected as a mutational cancer driver

RABEP1
Ensembl id ENSG00000029725
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RABEP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 7 6 0.52
Cutaneous melanoma No 7 4 1.08
Lung adenocarcinoma No 4 3 0.77
Renal clear cell carcinoma No 4 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 4 2 0.53
Esophageal carcinoma No 4 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Thyroid carcinoma No 1 1 0.31
Stomach adenocarcinoma No 4 1 0.62
Glioblastoma multiforme No 3 1 0.26
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence