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PXDN has not been detected as a mutational cancer driver

PXDN
Ensembl id ENSG00000130508
Mutated samples
Coding Sequence 179 (2.6%)
Protein Affecting 122 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PXDN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 23 6.23
Lung adenocarcinoma No 21 16 4.09
Stomach adenocarcinoma No 18 12 7.45
Uterine corpus endometrioid carcinoma No 14 11 4.78
Esophageal carcinoma No 15 11 7.53
Lung squamous cell carcinoma No 14 9 5.17
Head and neck squamous cell carcinoma No 12 7 1.87
Pancreas adenocarcinoma No 6 6 2.80
Renal clear cell carcinoma No 8 6 1.44
Colorectal adenocarcinoma No 10 5 2.18
Bladder carcinoma No 5 4 4.08
Breast carcinoma No 6 4 0.35
Serous ovarian adenocarcinoma No 4 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 1 1 0.48
Multiple myeloma No 2 1 1.45
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 2 1 4.35
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence