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PSG2 has not been detected as a mutational cancer driver

PSG2
Ensembl id ENSG00000242221
Mutated samples
Coding Sequence 75 (1.1%)
Protein Affecting 56 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PSG2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 24 6.50
Lung adenocarcinoma No 10 9 2.30
Lung squamous cell carcinoma No 8 8 4.60
Stomach adenocarcinoma No 4 3 1.86
Uterine corpus endometrioid carcinoma No 2 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 3 1 1.02
Breast carcinoma No 1 1 0.09
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Non small cell lung carcinoma No 2 0 0.00
Glioblastoma multiforme No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence