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PRRC2C has not been detected as a mutational cancer driver

PRRC2C
Ensembl id ENSG00000117523
Mutated samples
Coding Sequence 122 (1.8%)
Protein Affecting 91 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRRC2C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 17 4.61
Renal clear cell carcinoma No 13 11 2.64
Breast carcinoma No 11 10 0.87
Lung adenocarcinoma No 15 9 2.30
Uterine corpus endometrioid carcinoma No 11 8 3.48
Head and neck squamous cell carcinoma No 9 8 2.13
Lung squamous cell carcinoma No 8 6 3.45
Stomach adenocarcinoma No 6 5 3.11
Hepatocarcinoma No 7 3 3.33
Bladder carcinoma No 4 3 3.06
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 5 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Esophageal carcinoma No 1 1 0.68
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence