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PRDM8 has not been detected as a mutational cancer driver

PRDM8
Ensembl id ENSG00000152784
Mutated samples
Coding Sequence 23 (0.3%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRDM8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 5 5 0.44
Thyroid carcinoma No 3 2 0.62
Cutaneous melanoma No 3 2 0.54
Lung adenocarcinoma No 1 1 0.26
Stomach adenocarcinoma No 3 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Prostate adenocarcinoma No 2 0 0.00
Bladder carcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence