PQBP1 has not been detected as a mutational cancer driver

Ensembl id ENSG00000102103
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PQBP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 7 3 1.30
Breast carcinoma No 8 2 0.17
Cutaneous melanoma No 4 2 0.54
Serous ovarian adenocarcinoma No 3 2 0.63
Lung adenocarcinoma No 8 1 0.26
Medulloblastoma No 3 1 0.48
Stomach adenocarcinoma No 3 1 0.62
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 3 1 0.26
Lung squamous cell carcinoma No 2 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Head and neck squamous cell carcinoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence