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PPP6R3 has not been detected as a mutational cancer driver

PPP6R3
Ensembl id ENSG00000110075
Mutated samples
Coding Sequence 56 (0.8%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PPP6R3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 7 1.90
Uterine corpus endometrioid carcinoma No 4 4 1.74
Bladder carcinoma No 4 3 3.06
Breast carcinoma No 4 3 0.26
Colorectal adenocarcinoma No 3 3 1.31
Prostate adenocarcinoma No 2 2 0.82
Lung adenocarcinoma No 4 2 0.51
Hepatocarcinoma No 3 2 2.22
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 3 1 0.24
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence