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PPP2R5B has not been detected as a mutational cancer driver

PPP2R5B
Ensembl id ENSG00000068971
Mutated samples
Coding Sequence 57 (0.8%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PPP2R5B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 7 1.90
Lung squamous cell carcinoma No 6 4 2.30
Lung adenocarcinoma No 4 3 0.77
Breast carcinoma No 3 2 0.17
Renal clear cell carcinoma No 5 2 0.48
Neuroblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 6 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence