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PLA2G2D has not been detected as a mutational cancer driver

PLA2G2D
Ensembl id ENSG00000117215
Mutated samples
Coding Sequence 16 (0.2%)
Protein Affecting 10 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PLA2G2D gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 5 3 0.81
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 1 1 0.09
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 1 1 0.27
Lung adenocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence