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PIP4K2B has not been detected as a mutational cancer driver

PIP4K2B
Ensembl id ENSG00000141720
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PIP4K2B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 3 0.81
Lung squamous cell carcinoma No 5 2 1.15
Head and neck squamous cell carcinoma No 4 2 0.53
Lung adenocarcinoma No 4 1 0.26
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 2 1 1.02
Breast carcinoma No 2 1 0.09
Thyroid carcinoma No 2 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Multiple myeloma No 2 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Medulloblastoma No 2 0 0.00
Renal clear cell carcinoma No 4 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence