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PHF6 × Acute Lymphoblastic Leukemia ×

PHF6 is detected as a mutational cancer driver in Acute Lymphoblastic Leukemia

PHF6 reports in Acute Lymphoblastic Leukemia (ALL)

Cancer type details
Acute Lymphoblastic Leukemia
Cohorts 5
Samples 363
Mutations 202,546
Driver genes 28
Gene details
PHF6
Ensembl ID ENSG00000156531
Transcript ID ENST00000332070
Protein ID ENSP00000329097
Cohorts where is driver 1
Mutated samples 2
Mutated samples (%) 0.55
Mutations 4
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence