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PHF2 has not been detected as a mutational cancer driver

PHF2
Ensembl id ENSG00000197724
Mutated samples
Coding Sequence 57 (0.8%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PHF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 12 3.25
Stomach adenocarcinoma No 12 10 6.21
Lung squamous cell carcinoma No 4 4 2.30
Uterine corpus endometrioid carcinoma No 3 3 1.30
Small cell lung carcinoma No 2 2 2.90
Lung adenocarcinoma No 3 1 0.26
Breast carcinoma No 1 1 0.09
Head and neck squamous cell carcinoma No 4 1 0.27
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Bladder carcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence