Top
PCDHGB7 has not been detected as a mutational cancer driver

PCDHGB7
Ensembl id ENSG00000254122
Mutated samples
Coding Sequence 391 (5.8%)
Protein Affecting 55 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHGB7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 84 7 1.90
Lung adenocarcinoma No 35 6 1.53
Head and neck squamous cell carcinoma No 36 6 1.60
Stomach adenocarcinoma No 30 5 3.11
Esophageal carcinoma No 20 5 3.42
Breast carcinoma No 28 4 0.35
Prostate adenocarcinoma No 9 3 1.23
Bladder carcinoma No 15 3 3.06
Renal clear cell carcinoma No 10 3 0.72
Serous ovarian adenocarcinoma No 16 3 0.95
Colorectal adenocarcinoma No 19 3 1.31
Lung squamous cell carcinoma No 24 2 1.15
Uterine corpus endometrioid carcinoma No 26 2 0.87
Hepatocarcinoma No 2 1 1.11
Chronic lymphocytic leukemia No 5 1 0.34
Multiple myeloma No 2 1 1.45
Acute myeloid leukemia No 2 0 0.00
Medulloblastoma No 2 0 0.00
Pancreas adenocarcinoma No 3 0 0.00
Thyroid carcinoma No 4 0 0.00
Lower grade glioma No 5 0 0.00
Small cell lung carcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 9 0 0.00
Acute lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence