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PCDHGA11 has not been detected as a mutational cancer driver

PCDHGA11
Ensembl id ENSG00000253873
Mutated samples
Coding Sequence 332 (4.9%)
Protein Affecting 63 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHGA11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 71 13 3.52
Lung adenocarcinoma No 33 6 1.53
Lung squamous cell carcinoma No 19 6 3.45
Esophageal carcinoma No 19 5 3.42
Breast carcinoma No 24 4 0.35
Uterine corpus endometrioid carcinoma No 25 4 1.74
Stomach adenocarcinoma No 26 4 2.48
Colorectal adenocarcinoma No 16 4 1.75
Head and neck squamous cell carcinoma No 30 4 1.07
Bladder carcinoma No 10 3 3.06
Serous ovarian adenocarcinoma No 13 3 0.95
Pancreas adenocarcinoma No 3 2 0.93
Renal clear cell carcinoma No 9 2 0.48
Thyroid carcinoma No 4 1 0.31
Glioblastoma multiforme No 8 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 6 0 0.00
Hepatocarcinoma No 2 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 2 0 0.00
Lower grade glioma No 5 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence