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PCDHB13 has not been detected as a mutational cancer driver

PCDHB13
Ensembl id ENSG00000187372
Mutated samples
Coding Sequence 243 (3.6%)
Protein Affecting 70 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHB13 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 67 14 3.79
Lung adenocarcinoma No 32 8 2.05
Head and neck squamous cell carcinoma No 18 7 1.87
Lung squamous cell carcinoma No 20 6 3.45
Serous ovarian adenocarcinoma No 8 5 1.58
Colorectal adenocarcinoma No 13 5 2.18
Stomach adenocarcinoma No 17 4 2.48
Glioblastoma multiforme No 9 4 1.06
Bladder carcinoma No 4 3 3.06
Breast carcinoma No 11 3 0.26
Renal clear cell carcinoma No 3 3 0.72
Hepatocarcinoma No 4 2 2.22
Uterine corpus endometrioid carcinoma No 14 2 0.87
Small cell lung carcinoma No 6 2 2.90
Lower grade glioma No 2 1 0.59
Esophageal carcinoma No 5 1 0.68
Prostate adenocarcinoma No 2 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence