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PCDHB11 has not been detected as a mutational cancer driver

PCDHB11
Ensembl id ENSG00000197479
Mutated samples
Coding Sequence 132 (1.9%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHB11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 33 20 5.42
Lung adenocarcinoma No 22 13 3.32
Head and neck squamous cell carcinoma No 14 7 1.87
Breast carcinoma No 12 6 0.52
Lung squamous cell carcinoma No 8 5 2.87
Stomach adenocarcinoma No 7 4 2.48
Esophageal carcinoma No 5 4 2.74
Bladder carcinoma No 3 3 3.06
Renal clear cell carcinoma No 5 3 0.72
Serous ovarian adenocarcinoma No 5 3 0.95
Uterine corpus endometrioid carcinoma No 4 2 0.87
Small cell lung carcinoma No 3 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Acute lymphocytic leukemia No 2 2 1.64
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 1 1 0.51
Neuroblastoma No 2 1 0.48
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence